Howdy from Arizona! I’m 13.5 years clean from meth and rave drugs. 
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Welcome to the community. Congrats on your clean time.
For what it’s worth, most studies I know of are on the developmental neurotoxicity (effects on the young). And the number one offending ingredient for nicotine vaping is…
Nicotine.
Likewise for cardiovascular issues, etc.
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Alcohol 
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Cocaine and alcohol almost a week really struggling last few days
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Alcohol is the issue for me but I’m also abstaining from weed / edibles/ mushrooms for the foreseeable future. I’d like to live that straight edge lifestyle one day.
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Mostly cocaine with some alcoholism thrown in.
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Day one today Alcohol
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Life is long so was the list of drugs only alcohol now.
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These were the most problematic substances for me. Grateful to be free today:
17 years off meth
13 years off nicotine
10 years off extacy and opioids
650 days off cocaine/crack cocaine
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Almost 5 years clean from self harm. 
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Welcome to the community Brian
Great work on Starting day 1. Keep going strong …it does get easier
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Welcome to the community Miranda
5 years is amazing! 
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Thank you have no doubt i will be checking in everyday
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Today I’m sober from ANGER
4 months
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Alcohol too.
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Sugar, binge eating
But truly using all kinds of behaviours to numb the pain of existence, boredom and whatnot.
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I only have a timer for alchohol because that was my biggie. But back in the good ol’ days I abused coke, benzos, weed (I never liked it much tho) and ambiens (the memory blanks are insane on those). It was an anything to feel anything type situation. Now I’m completely sober of everything. Apart from my nicotine vape and the ridiculous amount of coffee I drink on the daily.
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